:root {
  --navy: #0f172a;
  --clinical: #2563eb;
  --alert: #dc2626;
  --paper: #f8fafc;
}

html { scroll-behavior: smooth; }

@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
}

html body {
  margin: 0;
  background: var(--paper);
  color: var(--navy);
  font-family: "Source Sans 3", "Segoe UI", sans-serif;
  line-height: 1.65;
}

html body h1,
html body h2,
html body h3,
html body h4,
html body .font-display {
  font-family: "Source Serif 4", Georgia, serif;
  line-height: 1.2;
  letter-spacing: -0.02em;
}

.skip {
  position: absolute;
  left: 1rem;
  top: -4rem;
  z-index: 80;
  background: #fff;
  color: var(--navy);
  padding: 0.5rem 1rem;
  border-radius: 0.375rem;
}

.skip:focus { top: 0.5rem; }

:focus-visible {
  outline: 2px solid var(--clinical);
  outline-offset: 3px;
}

[hidden] { display: none !important; }

@media (max-width: 767px) {
  nav[data-nav] { display: none; }
  nav[data-nav].is-open {
    display: flex;
    position: absolute;
    left: 0;
    right: 0;
    top: 100%;
    z-index: 40;
    flex-direction: column;
    gap: 0.35rem;
    background: #fff;
    border-bottom: 1px solid #e2e8f0;
    padding: 0.75rem 1rem 1.1rem;
    box-shadow: 0 12px 24px rgba(15, 23, 42, 0.08);
  }
}

details.nav-drop > summary {
  list-style: none;
  cursor: pointer;
}

details.nav-drop > summary::-webkit-details-marker { display: none; }

details.nav-drop[open] > summary { color: var(--clinical); }

.nav-panel {
  display: grid;
  gap: 0.35rem;
  padding: 0.45rem 0 0.2rem 0.75rem;
}

@media (min-width: 768px) {
  details.nav-drop { position: relative; }
  .nav-panel {
    position: absolute;
    top: calc(100% + 0.55rem);
    left: 0;
    min-width: 17.5rem;
    padding: 0.7rem;
    background: #fff;
    border: 1px solid #e2e8f0;
    border-radius: 0.75rem;
    box-shadow: 0 16px 40px rgba(15, 23, 42, 0.1);
    z-index: 30;
  }
}

.safety-alert,
.clinical-note,
.caution-note {
  border-radius: 0.9rem;
  padding: 1rem 1.15rem;
  margin: 1.25rem 0;
}

.safety-alert {
  background: #fef2f2;
  border: 1px solid #fecaca;
  border-left: 5px solid var(--alert);
  color: #450a0a;
}

.safety-alert strong.label,
.clinical-note strong.label,
.caution-note strong.label {
  display: block;
  font-size: 0.75rem;
  letter-spacing: 0.06em;
  text-transform: uppercase;
  margin-bottom: 0.25rem;
}

.safety-alert strong.label { color: var(--alert); }

.clinical-note {
  background: #eff6ff;
  border: 1px solid #bfdbfe;
  border-left: 5px solid var(--clinical);
}

.clinical-note strong.label { color: #1d4ed8; }

.caution-note {
  background: #fffbeb;
  border: 1px solid #fde68a;
  border-left: 5px solid #d97706;
}

.caution-note strong.label { color: #b45309; }

.prose-clinical h2 { font-size: 1.7rem; margin: 2.4rem 0 0.7rem; }
.prose-clinical h3 { font-size: 1.25rem; margin: 1.6rem 0 0.45rem; }
.prose-clinical p { margin: 0.8rem 0; }
.prose-clinical ul,
.prose-clinical ol { margin: 0.6rem 0 1rem; padding-left: 1.25rem; }
.prose-clinical li { margin: 0.35rem 0; }
.prose-clinical a { color: #1d4ed8; text-underline-offset: 2px; }

.matrix-wrap { overflow-x: auto; -webkit-overflow-scrolling: touch; }

.matrix {
  width: 100%;
  min-width: 920px;
  border-collapse: collapse;
  background: #fff;
  font-size: 0.92rem;
}

.matrix th,
.matrix td {
  text-align: left;
  vertical-align: top;
  padding: 0.8rem 0.75rem;
  border-bottom: 1px solid #e2e8f0;
}

.matrix th {
  background: var(--navy);
  color: #fff;
  font-weight: 600;
  position: sticky;
  top: 0;
}

.matrix tbody tr:hover { background: #f8fafc; }

.crumb ol { display: flex; flex-wrap: wrap; gap: 0.35rem 0.45rem; list-style: none; margin: 0; padding: 0; }

.finder-option {
  width: 100%;
  text-align: left;
  border: 1px solid #cbd5e1;
  background: #fff;
  border-radius: 0.8rem;
  padding: 0.85rem 1rem;
}

.finder-option:hover,
.finder-option[aria-pressed="true"] {
  border-color: var(--clinical);
  background: #eff6ff;
}

.pill {
  display: inline-flex;
  align-items: center;
  border-radius: 999px;
  padding: 0.15rem 0.55rem;
  font-size: 0.75rem;
  font-weight: 700;
  background: #e2e8f0;
  color: #0f172a;
}

@media print {
  .no-print { display: none !important; }
  .safety-alert { break-inside: avoid; }
  body { background: #fff; }
}